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Year Number of Results
1968 1
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1976 1
1977 1
1979 2
1980 2
1981 3
1982 3
1983 3
1984 3
1985 1
1986 7
1987 13
1988 17
1989 14
1990 9
1991 17
1992 14
1993 16
1994 14
1995 17
1996 18
1997 16
1998 13
1999 7
2000 13
2001 17
2002 12
2003 13
2004 11
2005 16
2006 9
2007 8
2008 8
2009 10
2010 8
2011 7
2012 13
2013 7
2014 11
2015 5
2016 14
2017 12
2018 9
2019 11
2020 7
2021 9
2022 12
2023 8
2024 8

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443 results

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Page 1
Folding molecular dynamics simulation of T-peptide, a HIV viral entry inhibitor: Structure, dynamics, and comparison with the experimental data.
Gkogka I, Glykos NM. Gkogka I, et al. J Comput Chem. 2022 May 30;43(14):942-952. doi: 10.1002/jcc.26850. Epub 2022 Mar 25. J Comput Chem. 2022. PMID: 35333419
Peptide T is a synthetic octapeptide fragment, which corresponds to the region 185-192 of the gp120 HIV coat protein and functions as a viral entry inhibitor. In this work, a folding molecular dynamics simulation of peptide T in a membrane-mimicking (D …
Peptide T is a synthetic octapeptide fragment, which corresponds to the region 185-192 of the gp120 HIV coat protein and funct …
Peptide T inhibits HIV-1 infection mediated by the chemokine receptor-5 (CCR5).
Ruff MR, Melendez-Guerrero LM, Yang QE, Ho WZ, Mikovits JW, Pert CB, Ruscetti FA. Ruff MR, et al. Antiviral Res. 2001 Oct;52(1):63-75. doi: 10.1016/s0166-3542(01)00163-2. Antiviral Res. 2001. PMID: 11530189
Peptide T, which is derived from the V2 region of HIV-1, inhibits replication of R5 and dual-tropic (R5/X4) HIV-1 strains in monocyte-derived macrophages (MDMs), microglia, and primary CD4(+)T cells. Little to no inhibition by peptide T was observed wi …
Peptide T, which is derived from the V2 region of HIV-1, inhibits replication of R5 and dual-tropic (R5/X4) HIV-1 strains in m …
NMR studies of peptide T, an inhibitor of HIV infectivity, in an aqueous environment.
De Dios AC, Sears DN, Tycko R. De Dios AC, et al. J Pept Sci. 2004 Oct;10(10):622-30. doi: 10.1002/psc.571. J Pept Sci. 2004. PMID: 15526711
This study investigated the degree of conformational order of two analogs of peptide T, one biologically active (D-Ala peptide T amide) and one inactive (D-Ala, D-Tyr peptide T amide) using nuclear magnetic resonance (NMR) spectroscopy in …
This study investigated the degree of conformational order of two analogs of peptide T, one biologically active (D-Ala pept …
Molecular dynamics simulation of HIV fusion inhibitor T-1249: insights on peptide-lipid interaction.
Martins do Canto AM, Palace Carvalho AJ, Prates Ramalho JP, Loura LM. Martins do Canto AM, et al. Comput Math Methods Med. 2012;2012:151854. doi: 10.1155/2012/151854. Epub 2012 May 22. Comput Math Methods Med. 2012. PMID: 22675399 Free PMC article.
Recent results indicate that T-1249, as in the case of related inhibitor peptide T-20 (enfuvirtide), interacts with membranes, more extensively in the bilayer liquid disordered phase than in the liquid ordered state, which could be linked to its effectiveness. ...
Recent results indicate that T-1249, as in the case of related inhibitor peptide T-20 (enfuvirtide), interacts with membranes, …
Randomized double-blind placebo-controlled trial of peptide T for HIV-associated cognitive impairment.
Heseltine PN, Goodkin K, Atkinson JH, Vitiello B, Rochon J, Heaton RK, Eaton EM, Wilkie FL, Sobel E, Brown SJ, Feaster D, Schneider L, Goldschmidts WL, Stover ES. Heseltine PN, et al. Arch Neurol. 1998 Jan;55(1):41-51. doi: 10.1001/archneur.55.1.41. Arch Neurol. 1998. PMID: 9443710 Clinical Trial.
BACKGROUND: Cognitive impairment is a common consequence of human immunodeficiency virus (HIV) infection, and dementia is one of the diseases that defines the acquired immunodeficiency syndrome. Peptide T (d-ala-peptide-T-amide) has been reported to bl …
BACKGROUND: Cognitive impairment is a common consequence of human immunodeficiency virus (HIV) infection, and dementia is one of the disease …
Effects of [D-Ala1] peptide T-NH2 and HIV envelope glycoprotein gp120 on cyclic AMP dependent protein kinases in normal and psoriatic human fibroblasts.
Liapi C, Takahashi N, Raynaud F, Evain-Brion D, Anderson WB. Liapi C, et al. J Invest Dermatol. 1998 Apr;110(4):332-7. doi: 10.1046/j.1523-1747.1998.00149.x. J Invest Dermatol. 1998. PMID: 9540970 Free article.
Peptide T exhibited a biphasic dose dependent response, with maximal effects on PKA noted at 10(-12)M peptide T. ...The presence of peptide T blocked this effect of the gp120 protein. These results indicate that peptide T an …
Peptide T exhibited a biphasic dose dependent response, with maximal effects on PKA noted at 10(-12)M peptide T. …
443 results